High-throughput phenotyping methods for quantifying hair fiber morphology
نویسندگان
چکیده
منابع مشابه
High-throughput hyperdimensional vertebrate phenotyping
Most gene mutations and biologically active molecules cause complex responses in animals that cannot be predicted by cell culture models. Yet animal studies remain too slow and their analyses are often limited to only a few readouts. Here we demonstrate high-throughput optical projection tomography with micrometre resolution and hyperdimensional screening of entire vertebrates in tens of second...
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* Corresponding author. E-mail address: [email protected] (T.E. Gr 1537-5110/$ e see front matter a 2011 IAgrE doi:10.1016/j.biosystemseng.2011.06.004 This paper describes the development of high-throughput measurement techniques allowing acquisition of phenotypical data describing maize roots. One of a maize root’s traits is the level of complexity, which was expressed in a Fractal Dimension ...
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The recent completion of the Human Genome Project has made possible a high-throughput "systems approach" for accelerating the elucidation of molecular underpinnings of human diseases, and subsequent derivation of molecular-based strategies to more effectively prevent, diagnose, and treat these diseases. Although altered phenotypes are among the most reliable manifestations of altered gene funct...
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A bold new effort to disrupt every gene in the mouse genome necessitates systematic, interdisciplinary approaches to analyzing patterning defects in the mouse embryo. We present a novel, rapid, and inexpensive method for obtaining high-resolution virtual histology for phenotypic assessment of mouse embryos. Using osmium tetroxide to differentially stain tissues followed by volumetric X-ray comp...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-021-90409-x